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Roger: You're not going to die.
Holmes: Roger. I'm 93.
Roger: I had a great uncle who lived to be 102.
Holmes: Well, then, that seals my fate. What are the odds that you would know two men who would live that long?
Roger: Well, I didn't actually know him.
Holmes: Ah. The iris. Amazing resilience. Enough light and they will grow
in the most uninhabitable regions, desert, cold, rock. Why do you suppose it is that something as small and insignificant as the iris should be so much stronger than we are? Perhaps they're less affected by what goes on around them.
Ann: And is that enough?
Holmes: It can be. If one is so fortunate as to find a place in the world. And another soul with whom one's loneliness can reside.
Roger: If you can't remember, then why couldn't the case have been a success like Dr. Watson wrote it?
Holmes: Because it was my last case. And if I'd brought it to a successful conclusion, I wouldn't have left the profession and spent 35 years here, in this place, away from the world! I chose exile for my punishment, but what was it for? I must have done something terribly wrong...And I've no evidence of what it was. Only pain, guilt... Useless, worthless feelings!
Ann: The dead are not so very far away. They're just...On the other side of the wall. It's us, on this side, who are, all of us so...
Holmes: Alone? I have been alone...All my life. But with the compensations
of the intellect.
Due to possibility of spoilers, suggest not to read quotes in general until after watching the film:
Roger: What is Royal Jelly?
Holmes: It's a special secretion of the worker bees. And it's royal because?
Roger: It feeds the queen.
Holmes: Bravo. It was the jelly's curative powers that prompted my monograph, The Value of Royal Jelly with Further Comments on the Potential Health Benefits of Prickly Ash.
Roger: What's that?
Holmes: Prickly Ash, … Well, in Japanese, Hire Sansho is the common word for Zanthoxylum piperitum. It's used to treat various degenerative diseases. Anaemia, circulatory conditions... Arthritis and... Hm. What's it called? Oh. Senility. That was a witticism.
Holmes: But surely it can't do me ill.
Doctor: In and of itself, no.
Holmes: You mean there might be side effects?
Holmes: Such as?
Holmes: … human nature was a mystery that logic alone could not illuminate. I had successfully deduced the facts of her case, but I had failed to grasp their meaning. Never had I felt such an incomprehensible emptiness within myself. Only then did I begin to understand how utterly alone I was in the world.
Holmes: The first thing to know is there's no danger. Bees aren't interested in harming you. Their only concern is self-preservation.
Roger: From people?
Holmes: They're much too clever for people. Their enemies are the weather, disease and predators. The wasp is their particular antagonist. Did you know that one wasp can kill 40 honey bees in under a minute?
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